Foo Fighters starts their North American tour soon and Grohl talks about making a tour commercial called “Hot Buns” – check out the video below, though NSFW. And yes, those are really Foo Fighters’ asses. No butt doubles here:

Eva Mendes also talks about cheating and betrayal and her viewpoint on threesomes.

Overall, Mendes may not believe in the institution of marriage, but she is a total romantic!

Chelsea Handler and 50 Cent dated casually, she explains: “”We dated. Very casually.”

Handler explained that 50 Cent is “fun. He’s a great guy.”

In fact, 50′s not what you’d expect: “He’s the complete antithesis of what you would imagine. He’s a sweetheart. He’s sweet, funny. He has a great sense of humor.”

Piers Morgan also asks Handler if she’s airbrushed on her newest book’s cover, and she responds, “Really? Fuck off… of course it’s airbrushed, everything’s airbrushed!”

Handler’s new book is stories from all of the victims of her practical jokes.

What’s next for Chelsea Handler? She likes writing books and being on TV, but says she’ll probably take a break from standup.

Hayden Panettiere also talks about her huge boyfriend, although Chelsea doesn’t ask how they have sex, which inquiring minds seem to want to know, given the size difference between Hayden and the boxer.

Chelsea Handler missed an opportunity for dirty talk, though she did bring up muff diving, so all’s not lost.

Rihanna also talks about working with Eminem and their performance at the Video Music Awards.

Former “Hills” star, Lo Bosworth appeared on Chelsea Lately to promote her new book The Lo-Down as well as let young Hollywood know that she is single and on the prowl. Chelsea also brought up her crush on former child star, Jonathan Taylor Thomas. You can watch the interview here.